So far, multiple sclerosis has been divided into 5 subtypes. Researchers are increasingly moving away from this model. Instead, MS appears to be a single entity, a dynamic process. Does this mean we can now say goodbye to the known progression forms?
For reminder: So far, 5 subtypes of MS have been distinguished:
- CIS,
- RIS,
- RRMS (sometimes also just called “RMS”),
- SPMS and
- PPMS.
But this classification is actually too short to adequately describe a patient’s multiple sclerosis at one time. Instead, it is known today that even in the case of classical RRMS (Relapsing-Remitting MS, i.e., relapsing MS), gradual deteriorations (keyword „smouldering“, i.e., smouldering MS) occur from the beginning. Time to think about a new model. – Prof. Mäurer goes into this in the following video:
This post was translated from German to English with the help of AI.






